Dishonored 2 - All Rune Locations

How to find all the Runes in Dishonored 2.

This guide will show you where to find all of the Runes in Dishonored 2. The runes in Dishonored 2 are incredibly important to Corvo and Emily, as they are the keys used to upgrade their abilities. If you want to get stronger in the game, you’re going to have to track down as many of the Runes as possible! Read on to learn where each Rune is located in Dishonored 2.

Mission 1: A Long Day in Dunwell

The first Rune in Dishonored 2 is found after you meet the Outsider toward the end of the chapter. Head behind the chair and along the fractured path. Collect the Heart to help find the other Runes.

Mission 2: Dreadful Wale

The Rune in Mission 2 of Dishonored 2 is found after beginning in the boat. Move outside and look over the side toward land. Beneath the ocean is a sunken vessel and inside this vessel, you will find the next Rune.

Mission 2: Edge of the World

Another Rune in Mission 2 is located shortly after you arrive on shore; look for the dead whale carcass along the wharf. You will find the Rune between the whale’s teeth.

The next Rune can either be stolen or purchased from the Black Market vendor. To purchase it, approach the vendor from the front. To steal it, make your way in from behind, steal his key, and use it to unlock the cabinet.

The next Rune can be found in the Overseer's office inside the safe. Open the safe by using the code found on the table.

Another Rune can be found in the sewer system. Head to where the water is rushing from behind a gate, you will need to shoot the blockage to release the Rune. Once you do, the water stream will bring the Rune right to you.

To track down the final Rune in Mission 2 of Dishonored 2, look for the large building in town with the “SEIZED!” sign draped over it. There, the Rune can be found on the opposite side of the street. Simply look for the man preaching, and once you find him, you'll see the Rune will on a workbench on the ground.

Mission 3: The Good Doctor

The first Rune in Mission 3 of Dishonored 2 is found in the dining area on the first floor. From the main entrance, go left to enter the dining area. Here, the Rune will be pinned to the wall above a table. Keep an eye out for guards in this location.

To find the next Rune, start at Hypatia’s Office and head down to the third floor. Unlock the Recuperation Room using the key you found earlier in the mission. The Rune will be located in a Bloodfly nest just after you open the door.

The next Rune will be near an Outsider Shrine in the same building as Hypatia’s Office. You will need to go right from Hypatia’s Office, outside, follow the terrace along, then head back into another small section of the building. Use your Heart to locate the shrine and the Rune.

Another Rune can be found above Hypatia’s Office. Go outside and climb the building. Look for the pipe that leads up to an open circular window. Head through the window and find the Rune on a workbench to your left.

The final Rune in Mission 3 of Dishonored 2 is located in the basement of the building. In order to access the basement, you will need to ride the elevator as high as it can go, climb out through the hatch in its roof, climb the rest of the way up using the inside of the elevator shaft, and then make your way into the upper room.

Once there, call the elevator up and cut its cables to send it crashing down. Next, carefully make your way down the inside of the elevator shaft, enter the elevator through the hatch, and climb through into the basement. There, you will find the Rune to the left on a shelf next to a painting.

Mission 4: The Clockwork Mansion

The first Rune you will find in Mission 4 of Dishonored 2 is located in a Bloodfly-infested building at the start of the mission. Locate the building with the barricades blocking the entrance. Enter the building, then make your way through the winding and blocked halls until you reach the second floor. The Rune is on an Outsider Shrine.

The next Rune in Dishonored 2 can be purchased or stolen from the Black Market vendor.

Another Rune is located in the Lower District, be sure to keep an eye out for the tracks and gang members. The Rune will be underneath an upside down table on the ground.

To find this next Rune, you will need to go to the Upper District and locate a building with a second-story balcony with an open door. Use Far Reach or Blink to gain access to this balcony. Move through the house and into the back office to find the Rune in the desk cupboard.

The final Rune in Mission 4 of Dishonored 2 is located in Jindosh’s Laboratory. Use the Bay 2 terminal to bring up the Anatomy Platform. Once the platform is raised, you’ll find the Rune on the desk.

Mission 5: The Royal Conservatory

The first Rune in Mission  5 of Dishonored 2 can be purchased or stolen from the Black Market Vendor. In order to steal the Rune, you will need to enter the Black Market from underground.

The following Rune is located near an Outside Shrine. Track down the building painted in red, scale the building, then use Blink or Far Reach to access the balcony across the way. Be careful of the traps inside. Move to the next floor up by using the fallen ceiling as a ramp. The Outsider Shrine and Rune located are amidst some flowers.

In order to find the next Rune, you will need to find the Archive Key from the basement of the Royal Conservatory. It will be hanging from a message board near mailboxes. Use this key to unlock the gate next to a painting of a gorilla. The Rune will be inside the gate, to the right, and inside a glass case. Break the case to retrieve the Rune.

This next Rune is found on the second floor of the Royal Conservatory. At the front of the building will be a room; enter the room, look for the corner that is overgrown with plants, and you will discover the Rune sitting on some pillows on the vines.

To find the last Rune in Mission 5 of Dishonored 2, make your way to the terrace above Ashworth’s Office. Once there, head up the red-carpeted stairs and into the next area. To your right will be a large tree and behind the treeon a candle-covered benchis the Rune.

Mission 6: Dust District

To find the first Rune in Mission 6 of Dishonored 2, leave the building where you speak with Captain Foster, head down to the street, and break through the door. Once inside, find a locker on its side. Open this locker to retrieve the Rune.

The following Rune can be found inside the building with the word “SEIZED!” painted on the outside. Use the first-floor balcony to gain access to the building. There, the Rune will be in a side room, behind a partition, and inside a table.

This next Rune is located on an Outsider Shrine in the Crone’s Hand Saloon. Head upstairs to the second floor, enter the room on your right, and there you will find the Rune in the back room on the Outsider Shrine.

The final Rune in Mission 6 of Dishonored 2 is found in the Overseer's building. Head upstairs to the locked evidence room, and use the key found in the barracks or medical room to gain access. On the ground is a lock, once you've unlocked this with your key, you will find the Rune inside. 

Mission 7: Crack in the Slab

The first Rune in Mission 7 of Dishonored 2 is located on the first floor of Aramis Stilton’s Mansion. Head up the steps, through the door in front of you, turn left, and find the Rune on the ground below a table.

This next Rune requires a few more steps to acquire. First, you will need to collect the valve wheel in the basement. Pick up the wheel and throw it through the hole in the wall beside it. Move through time, jump through the hole, and switch back to the other instance.

Pick up the wheel, place it near the metal bars, and jump through time again. Pick up the wheel while underwater and place it on the wall. Next, hold the appropriate button to drain the water from the room. When the room is drained, look for the Rune on a stack of boxes.

To find the final Rune in Mission 7 of Dishonored 2, you will need to head upstairs in the present and move into the room at the opposite end. On your left will be a blocked passageway; jump through time in order to reveal an open window. Next. walk out the window onto the metal archway that has fallen and into the open window. Transition through time until you see the Rune beside the chair and mannequins.

Mission 8: The Grand Palace

To find the first Rune in Mission 8 of Dishonored 2, find the apartment building and the windmill, climb to the roof, and get to the balcony below. There, the Rune can be found in the bathroom.

The next rune is found by gaining access to the tunnel under the building with SEIZED!” painted on it. Head around the back, past the rear of the Black Market, and find the partially boarded up tunnel. Destroy the planks and head inside to retrieve the Rune from the Outsider Shrine.

The next Rune can be found in an underwater passage beyond the Duke’s Shrine. Head downstairs and search for a shelf with a metal frame made of diamonds; there, you will find a small button on the shelf that will open a secret passage when pressed. Move through the secret passage, head left, and crawl through the small hole in the wall into the submerged passage. Swim below the water and down the stairs, where you will find the Rune on a bench underwater.

To find the final Rune in Mission 8 of Dishonored 2, head upstairs to the third floor and look on the Duke’s desk to find the combination of the safe. Use the elevator to reach the ground floor, turn right, go through the door on the right, turn right again, and enter the door. Move up the steps, open the next door, move deeper into the room, and use the combination to unlock the safe and find the Rune.

Mission 9: Death to the Empress

The first Rune in Mission 9 of Dishonored 2 is located just after you've begun the mission. Head to the Black Market and either purchase the Rune from the vendor or steal it.

The next Rune is a few buildings behind the Black Market. You will need to scale the building and locate the Outsider Shrine to claim this Rune.

Another Rune can be found just before Dunwell Tower; here, you can find it at the very top of a building.

The final Rune in Dishonored 2 can be found after you enter Dunwell Tower. Locate the security room in the cellar, then look for the pipes. On top of these pipes, you’ll find the final Rune.

You will now be able to upgrade Corvo or Emily as much as you want thanks to all these Runes. If you followed this guide you should now be able to locate all of the Runes in Dishonored 2.

Sam Chandler

Australian writer who has a penchant for Souls games, an addiction to Destiny, and a love for the indie.

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